Therapeutic Plasma Exchange
An exciting high-level blood filtration technique
Therapeutic Plasma Exchange (TPE), also known as Therapeutic Plasmaphereis has been a powerful tool for treatment of critically-ill patients in hospital settings, for many years. Now the same technology is available to you in an outpatient setting, at Lifespan Health.
TPE is currently being studied for a wide variety of potential benefits, including removal of inflammatory mediators, chemicals, plastics, cellular waste, immune complexes, and other unwanted plasma-based toxins.
Call to schedule a free consultation 952-546-5322
Detoxification
Improve health parameters by
decreasing your toxic burden
Lifespan Health is offering this advanced therapy to those who are experiencing chronic inflammation, environmental toxicities, and long-term effects of infectious syndromes--as well as to clients who want to take a proactive approach to wellness and health optimization
The Process
Therapeutic Plasmapheresis is the cornerstone therapy of comprehensive protocols designed to meet your unique health needs and goals.
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Each protocol follows a logical, collaborative, diagnostic and treatment framework:
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1. ASSESSMENT
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Includes a comprehensive medical history review, physical examination, evaluation of blood biomarkers, measurements of toxins. Then we make specific treatment recommendations, assuring that the plan aligns with your expectations.
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2. THERAPEUTIC PLASMA EXCHANGE (TPE)
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One or more monthly sessions
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3. NUTRIENT SUPPORT
Utilizing a combination of oral and IV nutrients, specifically designed to augment your TPE procedures, and achieve the very best results.
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4. RETEST
Compare post-treatment toxin levels and biomarkers with the pre-treatment results.
The Protocols
Each of the Lifespan Health Plasma Exchange protocols are developed by and overseen by Dr. Mark Rawson. The procedure is performed by highly-trained RNs in a comfortable clinic setting.
DETOXIFICATION
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In-person or virtual appointment with Dr. Mark Rawson.​
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Comprehensive blood biomarkers and toxin level testing​
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3-5 monthly TPE sessions with supportive IV and oral nutrients and toxin-specific compounds​
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3 IV ozone therapy sessions (single-pass or EBOO)
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6-month supply of ongoing oral support nutrients and toxin-specific compounds​
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Follow up testing of biomarkers and toxin levels​
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CHRONIC FATIGUE
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In-person or virtual appointment with Dr. Mark Rawson.​
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Comprehensive blood biomarkers and toxin level testing ​
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3-5 monthly TPE sessions with supportive IV and oral nutrients ​
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Follow up testing of biomarkers ​
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May be incorporated into our chronic fatigue recovery program with additional therapeutic modalities such as hyperbaric oxygen therapy, advanced IV therapy protocols (NAD+, NR, methylene blue,..) and peptide therapies.
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HEALTH OPTIMIZATION
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In-person or virtual appointment with Dr. Mark Rawson.​
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Comprehensive blood biomarkers and toxin level testing​
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3-5 monthly TPE sessions with supportive IV and oral nutrients and toxin-specific compounds​
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3 IV ozone therapy sessions (single-pass or EBOO)
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6-month supply of ongoing oral support nutrients and toxin-specific compounds​
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Follow up testing of biomarkers and toxin levels​
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The Procedure
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Blood is removed
After a complete medical evaluation and a detailed explanation of the procedure, you get comfortable in our plasma exhange suite.
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In a continuous process, blood is withdrawn...
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Blood components
are separated
By a complex centrifuge process, plasma is separated from the other blood components.
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The plasma contains numerous toxic substances that will be eliminated from your body.
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Blood + Replacement
Solution is reinfused
By a complex centrifuge process, plasma is separated from the other blood components.
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The plasma contains numerous toxic substances that will be eliminated from your body.
Plasma (with toxins)
is discarded
This plasma is automatically separated into bags, and prepared for disposal.
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The Science
What does the research and clinician experience reveal about
therapeutic plasma exchange?
Research Studies:
A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study. Boada M, López OL, Olazarán J, et al. Alzheimer's Dement. 2020; 16: 1412–1425. See study...
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Plasma Exchange in Alzheimer's Disease. Lucas Rohrer, et al. Transfusion Medicine Reviews 37 (2003) 10-15.
See study...
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Can serial therapeutic plasma exchange remove synthetic chemicals from humans? Paul Savage, Paul S. Anderson, et al. Medical Hypotheses 198 (2025) 111630. See study...
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Old plasma dilution reduces human biological age: a clinical study. Daehwan Kim, et al. GeroScience (2022) 44:2701-2720. See study...
In the Media:
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Videos:
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Questions & Answers
Is Plasma Exchange covered by insurance?
Unfortunately, plasma exchange procedures are not covered by most health insurance carriers. We are happy to provide you with a superbill to submit for reimbursement, if you would like to try.
Does Lifespan offer financing for TPE procedures and packages?
Yes, we offer financing options: 1. You may pay 50% of the cost initially, and then the remaining balance over a 90-day period. 2. You may utilize one of our 3rd-party financing partner programs.
Are Plasma Exchange, Plasmapheresis and Apheressis the same thing?
While all three involve removing and separating blood, there are key differences:​ Aphersis refers to procedure where blood is removed and separated into components, with one or more components removed.​ Plasmapheresi refers to small volume plasma removal, without returning replacement fluid (e.g. plasma donation) Plasma Exchange refers to the large volume plasma removal, followed by replacement of of a fresh plasma substitue fluid (albumin + saline).
How long does a plasma exchange treatment take?
The plasma exchange treatment itself takes about 90 minutes. However, allow for 3-4 hours to accomadate intake activity, vascular access and post-treatment observation.